NODICT 50 MG
Inhouse product
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$10.00 -
$2.75
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$2.75
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$2.75
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$2.75
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Introduction
NODICT 50 MG, containing the active ingredient Naltrexone,
is primarily used in the treatment of opioid and alcohol dependence. As part of
the opioid antagonist class, Naltrexone works by blocking the euphoric and
sedative effects of substances like alcohol and opioids. This medication is
integral in preventing relapse in individuals undergoing detoxification and
rehabilitation.
This article will discuss the various aspects of NODICT 50 MG,
including its mechanism of action, therapeutic uses, dosage, side effects,
precautions, and interactions.
Mechanism of Action
Naltrexone, the key ingredient in NODICT 50 MG, is a competitive
antagonist of opioid receptors, particularly at the mu, kappa, and delta opioid
receptors. Its mechanism of action involves:
- Blocking
opioid receptors: Naltrexone binds to opioid receptors in
the brain, preventing opioids like heroin or prescription painkillers from
binding to these sites. By doing so, it negates the pleasurable effects
(euphoria and relaxation) associated with opioid use.
- Inhibiting
dopamine release: When opioids bind to opioid receptors,
they typically cause the release of dopamine, which leads to the sensation
of pleasure. Naltrexone prevents this process, diminishing the desire to
use opioids.
- Alcohol
dependence treatment: While the exact mechanism in alcohol
dependence is not fully understood, Naltrexone is believed to reduce the
rewarding effects of alcohol by inhibiting the release of dopamine in the
brain's reward pathway.
Dosage and Administration
The standard dosage for NODICT 50 MG varies based on the condition
being treated and the individual’s health status. It's important to follow the
doctor's guidance on how to use Naltrexone safely.
1. For Opioid Dependence:
- The
usual adult dosage is 50 mg per day.
- Treatment
should be initiated after the patient has undergone detoxification and is
opioid-free for at least 7-10 days.
- Patients
are tested with a Naloxone challenge test to ensure they are
opioid-free before starting the medication, as taking Naltrexone while
opioids are still in the system can precipitate acute withdrawal symptoms.
2. For Alcohol Dependence:
- The
usual recommended dose is 50 mg per day, starting after a person
has abstained from alcohol for several days.
- The
treatment duration may vary but typically lasts for 12 weeks or longer,
depending on the patient's response and treatment goals.
Side Effects
While NODICT 50 MG is generally well-tolerated, it may cause side
effects in some individuals. Common side effects include:
Common Side Effects:
- Nausea
and vomiting
- Headache
- Dizziness
- Fatigue
- Nervousness
or anxiety
- Joint
and muscle pain
Serious Side Effects:
- Liver
toxicity: High doses of Naltrexone can lead to hepatotoxicity,
especially in patients with pre-existing liver conditions.
- Allergic
reactions: Symptoms like rash, swelling, and difficulty breathing
require immediate medical attention.
- Depression
and suicidal thoughts: In rare cases, some individuals may
experience changes in mood, including depression and suicidal thoughts.
Precautions and Warnings
Before starting treatment with NODICT 50 MG, it is essential to
consider certain precautions and warnings to ensure the safe use of the
medication.
Liver Function
- Naltrexone
can cause liver damage, so patients with pre-existing liver conditions
(e.g., hepatitis, cirrhosis) need close monitoring.
- Routine
liver function tests are advised before and during treatment.
Opioid Use
- Patients
should be completely free of opioids for at least 7-10 days before
starting NODICT 50 MG.
- Any
concurrent use of opioids while on Naltrexone can lead to withdrawal
symptoms or reduce the effectiveness of the drug.
Pregnancy and Lactation
- The
safety of Naltrexone in pregnant women is not fully established. It should
only be used during pregnancy if the potential benefits outweigh the
risks.
- Caution
is also advised for breastfeeding women, as it is not known if Naltrexone
passes into breast milk.
Mental Health
- Patients
with a history of depression or suicidal ideation should be monitored
closely, as Naltrexone may worsen mood symptoms in some individuals.
How to Store NODICT 50 MG
- Store
the medication at room temperature, away from moisture and heat.
- Keep
the tablets in their original container, out of reach of children.
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$10.00
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$2.75
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$2.75
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$2.75
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$2.75
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