TIZAN 2MG
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Introduction
Tizan 2mg
masked Film [treatment of vaccine composition] Drug - The pharmaceutical
medication introduced in this section is the treatment if vaccinated with a
product used as a muscle relaxant. It is most often used as a muscle relaxant,
relieving clenching because of neurological disorders or muscles being
stretched through overuse. Tizan 2mg contains the active ingredient, tizanidine
hydrochloride which is a short-acting muscle relaxant. In this article, we
provide a complete investigation of the uses and mode of action; also discuss
about dosage regime along with side effects as well as relevant other aspects.
Composition and Mechanism of Action
Tizan 2 contains tizanidine hydrochloride as an active ingredient. Tizan 2mg every tablet with the dosage of 2mg TIZANIDINE.
Mechanism of action
Tizanidine is an alpha-2 adrenergic agonist that has central nervous system depressant properties. Through an increase of presynaptic inhibition on the motor neuron, decreasing pre-synapse release of excitatory amino acids. Such an effect would inhibit the repetitive circuits responsible for muscle spasticity in polysynaptic reflex pathways. Therefore, tizanidine primarily lowers the synaptic release of these neurotransmitters and therefore lessens spasticity (through decreased obligatory resistance to passive movement) rather than reduces muscle stiffness.
Dosage and Administration
General
Dosage Guidelines
The dosage of Tizan 2 mg must be individualized according
to the patient's requirements and response. It is initially prescribed in a
dose of 2 mg, and that can be gradually increased by increments which average
about 2 to 4 mg until the therapeutic effect comes down. The cumulative daily
dose should not exceed 36mg.
Administration
You should take Tizan 2mg tablets by mouth and with or
without food. To prevent variations in absorption, doses should be taken with
meals on a fairly consistent timing schedule.
Titration and Maintenance
1.
Initial:
2mg, to be given up to three times a day.
2.
Dose titration:
Titrated at increments of 2mg to -4 mg q1-4 days
3.
Effective dose:
8 to 24 mg/day in divided doses, but provided three or four times daily as the
salt (ER capsule and ER tablet recommended)
4.
MAXIMUM DOSE:
Daily dose should not exceed 36mg.
Side Effects
All
medicines have side effects, Tizan 2mg is a medicine that also has some common
and serious S/Es. The nature of the side effects may differ in each patient,
from mild to severe.
Common Side Effects
1.
Drowsiness
2.
Dry mouth
3.
Weakness
4.
Fatigue
5.
Dizziness
6.
Drop in the blood pressure
(Hypotension)
7.
Bradycardia (slow heart rate)
Serious Side Effects
1.
Liver abnormalities: Monitor liver
enzymes regularly.
2.
Rare, but serious side effects
include hallucinations or delusions which should be treated immediately
3.
Common symptoms of an allergic
reaction may include rash, itching, swelling, severe dizziness trouble
breathing.
Precautions and Warnings
1.
If you do not have a full pill,
your capsules can also be opened up and put over the divided amount of
applesauce. Liver function tests must be conducted both to start treatment and
periodically during therapy.
2.
Renal Impairment: Monitor patients
with renal impairment for adverse effects; dose adjustments may be required.
3.
Use in Pregnancy and Lactation:
Tizanidine should be administrated during pregnancy only if the potential
benefit justifies to possible fetus risk.
4. Reproduction studies performed in pregnant rats at doses equivalent to (human dose) and 10 times the maximum recommended human dose based on a mg/m (2) basis revealed no evidence of developmental abnormalities, however, category C teratogenic effects were reported following administration to rabbits. There is inadequate information available on the use of Tgama Tablet during lactation.
Overdose
Overdosage
can cause significant sedation, hypotension and bradycardia. Symptoms of
tizanidine overdosage include: [See Warnings and Precautions.] An overdose
should be treated as symptomatic and supportive. If a recent overdose, stomach
wash and activated charcoal are used.
Storage
Keep Tizan 2mg tablets at room temperature away from moisture and heat. The rearming mechanism discriminates against children and animals.
Conclusion
Tizan 2mg is a useful medicine to treat muscle spasticity associated with neurological disorders. However, the efficacy of this modulator needs to be measured against its adverse effects as well as drug counter-reactions. While minimizing risks, which underscores a good starting cliche when it comes to all walks of medicine: there is no one-size-fits-all. Patients should be appropriately counseled on the common side effects and encouraged to take their medicine as directed. The safe and effective use of Tizan 2mg is available only with the guidance of a healthcare professional.
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