Inhouse product
Indications of Migraine Prophylaxis:
Sibelius is usually given
to help prevent migraine attacks. It is not a treatment for acute migraine
attacks but decreases the frequency, duration, and severity of migraines over
time. Vertigo: It is also useful in the management of vestibular disorders like
vertigo (a state where one experiences dizziness, spinning sensation, and loss of
balance). Other Uses: Sibelium may also be used for other conditions not listed
in this medication guide (see Indications/Sidelines), despite persuasion not being the primary use of Sibelium.
Dosage and Administration Dosage Adults:
The usual initial dose to prevent migraines is 10 mg once a day in
the evening. In the case of elderly patients, the dose is to be decreased up to 5
mg daily.
Side Effects Common Side Effects
Drowsiness Weight gain Increased appetite Gastrointestinal
discomfort Dry mouth Serious Side Effects Depression Extrapyramidal syndromes
(e.g., tremours, rigidity) Fatigue Muscle pain Hypersensitive responses like
breakouts, irritation
Precautions and Warnings Contraindications Allergy:
Patients with
hypersensitivity to Flunarizine or any other components present in the medicine
should not take Sibelium.
Depression:
Sibelium may worsen depression so caution should be exercised with
patients having a history of depressive disorders. Flunarizine can make the
symptoms of Parkinson's disease worse and should be avoided by individuals with
this condition.
Drug Interactions Potential Interactions Central Nervous System
Depressants:
The sedative effects of Flunarizine may be seen faster when used
with alcohol, barbiturates, or other hypnotic agents. Restasis is
contraindicated in patients with a history of an allergic response to any compound
present in it and effectively interacts if used with beta-blockers due to the
combined effect resulting in enhanced risk of the occurrence of serious
cardiovascular episodes. Concurrent administration with some antidepressants
can enhance the risk of adverse CNS effects Anaesthetics and neuromuscular blockers...
Clinical Efficacy Migraine Prophylaxis Generics) is approved for
the prophylaxis of headache and many clinical trials have shown it to be
effective in significantly reducing both the frequency as well as severity of
migraine attacks happening in patients. This is especially helpful for those
who have failed the other prophylactic medications. Treatment of Vertigo
Flunarizine is a proven effective drug to treat vertigo symptoms, especially in
cases related to vestibular disorder. Balancing the vestibular system,
minimizing vertigo
Counsel patients about the risks and benefits associated with
renal impairment. Adherence to Therapy Dosage And Usage Follow-Up Patients
should be instructed to take Sibelium regularly as prescribed so that they will
obtain the best results.
Side Effects:
Patients should be instructed to immediately report any unusual or
severe side effects to their healthcare provider Lifestyle.
Modifications of Diet and
Exercise:
Patients must be instructed to adhere vigorously to diet and exercise
habits to avoid the added weight gain from Sibelium.
Not to drink alcohol: Patients should not take any sort of liquor, as it can enhance the sedative effect of medication.
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