SEROFLO INHALER 125 MCG
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What is SEROFLO Inhaler 125mcg (Salmeterol Fluticasone)?
How do you use Seroflo Inhaler 125 mcg (fluticasone propionate and
salmeterol)?
It consists of two active substances salmeterol and fluticasone propionate. Fluticasone and
salmeterol are a Drug Maintenance Help for Chronic Obstructive Pulmonary
Disease with High Risk. Disclosure Salmeterol pitted against the press side is something that they call a long-acting beta2-adrenergic agonist (LABA).
Long-term
use of Fluticasone propionate (a corticosteroid which can help to reduce
inflammation in your airways) Composition and Formulation SEROFLO Inhaler Each
actuation contains Salmeterol (as xinafoate)125 mcg Fluticasone Propionate
125mcg Box.
Salmeterol
Mechanism of Action
- Salmeterol
is a long-acting beta2-adrenergic agonist. This leads to the activation of
beta2-adrenergic receptors in bronchial smooth muscle which causes a relaxation
effect thus having a direct jet impact on lowering airway resistance. This can
help relieve symptoms of wheezing, shortness of breath, cough, and chest
tightness as it decreases bronchospasm for up to 12 hours.
- Abstract
Topical fluticasone propionate is a synthetic glucocorticoid with high
anti-inflammatory potency. It acts via inhibition of these types of inflammatory
cells (mast cell, eosinophils, and neutrophil) activation as well as
production/secretion release from pro-inflammatory mediators such as histamines/eicosanoid cytokinesis [13].
- That will
decrease the inflammation, swelling, and irritation in these airways and keep
them open for a healthier patency of lung pathways allowing more oxygen to go to
the body cells. which reduces RR AKA hyperventilation protecting against
repeated asthma/COPD exacerbations.
- Dose Adults
and adolescents (12 years of age and over)1 inhalation twice daily. The
maintenance dose should be reduced to the lowest effective dosage as soon as
asthma control is achieved Adults 1 inhalation twice daily TOP Usage should be
individualized & adjusted based on the patient's clinic situation.
- Contraindications
Which patient should not take Seroflo Inhaler Salmeterol, fluticasone
propionate, or any of the excipients. COPD or asthma acute exacerbations if in
need of aggressive measures (e.g., status asthmaticus)
Asthma
Dosing and Administration Adult or Adolescent (12 years of age and older): One inhalation twice daily. When
asthma control is maintained, this should then be reduced to its minimal
effective dose.
COPD Adults: 1 puff inhaled BID Dosage must be
individualized based on patient response and severity of clinical events. Who
should not take Seroflo Inhaler Contraindications Salmeterol, fluticasone
propionate or any of the excipients listed in Section 6.1 (Hypersensitivity).
- Used for the
early management of status asthmaticus or other acute episodes when inhaled
adrenergic bronchodilators are needed, and time does not allow assessment before the institution of therapy.
- Pharmacokinetics
Salmeterol Salmeterol is absorbed locally in the lung; so, plasma levels are
not predictive of therapeutic response.
Metabolism: Extensive hepatic via CYP3A4 to α-hydroxy
salmeterol.
Excretion: Facial; via extensive
liver-metabolism. Consequently, the systemic absorption of fluticasone
propionate is very low or undetectable thus minimizing unintended side effects
due to its extensive first-pass hyperbolic and intestinal metabolism.
Complete the
sentence: Metabolism
is primarily catalyzed by CYP3A4 with this ending comment... (into inactive
metabolites) Faces (metabolites) Clinical Efficacy Asthma Seroflo Inhaler has
been demonstrated for the treatment in clinical trials to improve lung function
and reduce asthma symptoms, including during the night and early morning;
associated with bronchodilation nearing peak action at 2 hours after dosing);
treat exercise-induced asthma [the combination is currently approved] long-term
prophylaxis of severe COPD mild-to-moderate stable non-atopic intermittent or
persistent topical corticosteroid unresponsive. This has been found to lead to
better asthma symptom control as compared with inhaled corticosteroids alone.
Conclusion
Seroflo
Inhaler 125 mcg by Cipla for the treatment of asthma and COPD By acting on both
the causes of bronchoconstriction and inflammation associated with these
respiratory diseases, it ensures proper control which leads to a better quality
of life for patients.
All the
same, this remedy must be taken strictly under medical supervision: Side effects of Vimax Special The
drug is contraindicated for use in patients with hypersensitivity to one or
more constituent components of a vitamin complex. Constant, scheduled
monitoring is important for the best therapeutic results. Whether the healthcare
providers looking to prescribe Seroflo Inhaler 125 mcg would get a very good
insight into its use, advantages, and precautions with this comprehensive overview
along with including further hints leading them into effective prescription maneuvering
is yet to be decided by reading through as we offer enough avail opportunities.
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