HYPNITE 1 MG TAB

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TrustUs

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Pharmacology Action

The active ingredient of HYPNITE-1, zolpidem tartrate acts to increase the body's natural inhibitor of GABA at the GABA-A receptor, a neurotransmitter in the central nervous system. GABA is an inhibitory neurotransmitter, providing calming effects, such as sleep induction. Zolpidem acts selectively on GABA-A receptors in the omega-1 receptor subtype which results in its sedative effect.

The peak plasma concentrations, T max, were observed at 1.5 to 2 hours), and are widely (>92%) distributed in blood and tissues; good evidence exists that it crosses blood-brain barriers. Zolpidem is rapidly metabolized to inactive metabolites, which are eliminated mainly by renal excretion.

Excretion: Most of it undergoes renal excretion, with an elimination half-life of 2-3 hours.

Uses of HYPNITE-1

 

HYPNITE-1 is used to treat Insomnia (Not having enough sleep) which may cause you issues to slide in sleep. This is useful for helping patients get to sleep faster, reducing the frequency and duration of middle-of-the-night wakings, and improving the consolidation of sleep. This implies that due to its fast-paced impact, it is useful for patients who find difficulty in falling asleep.

  

Indications

 

Primary insomnia with onset problems Short-term treatment of insomnia Dosage and Administration of Yohimbine

 

Dosage: In adults, an initial dosage of 5 to 10 mg once per night immediately before sleep is recommended. Dosage should be individualized according to patient response and tolerability. Lower dose - to decrease the chance of side effects in a frail or elderly patient, provide 5 mg daily.

 

However, to achieve maximum results or effect of HYPNITE-1, it should be administered on an empty stomach. The tablet should be taken with a glass of water, follow the given instructions, and must not chewed crushed, or committed. Patients are required to get 7-8 hours in bed; otherwise, daytime impairment is expected.

 

Side Effects

 

Common Side Effects:

 

  • Drowsiness
  • Dizziness
  • Headache
  • Upset stomach (nausea or diarrhea)
  • Fatigue

 Precautions and Warnings

 

  • Pregnancy: HYPNITE-1 should be used in women who are pregnant only if the potential benefit justifies the potential risk to the fetus. 12:21 Lisa Zolpidem Pregnancy Category C; zolpidem is secreted in breast milk, caution advised with breastfeeding mothers Special populations Geriatric No dose adjustment necessary, but the premature hypotensive or sedative responses (MGHB and correspondingly for those less than 30 minutes later, primarily to too much discomfort because of anemia) Falls should not be used in geriatric patients more than the recommended limits into a meal.
  • Dependence: Zolpidem has the potential for abuse; use caution in patients with a history of substance abuse (also see Previous Substance Abuse under Cautions). Adj. Renal or hepatic impairment (potential dose adjustment) (consider: Dose adjustment is likely to be needed in impaired renal and hepatic function.)

 Storage and Handling


Storage of HYPNITE-1 Tablets Store medicine out of the reach of children and pets

Conclusion

This study demonstrated that HYPNITE-1 was effective when used for the short-term management of insomnia, as it improved both sleep quality and duration in patients. One is that it must be selected in a patient-specific fashion, and care must be taken to avoid both interactions and side effects so if appropriate, this may eventually lead to increased use

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