HYPNITE 1 MG TAB
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Reviews & Ratings
Pharmacology
Action
The active
ingredient of HYPNITE-1, zolpidem tartrate acts to increase the body's natural
inhibitor of GABA at the GABA-A receptor, a neurotransmitter in the central
nervous system. GABA is an inhibitory neurotransmitter, providing calming
effects, such as sleep induction. Zolpidem acts selectively on GABA-A receptors
in the omega-1 receptor subtype which results in its sedative effect.
The peak
plasma concentrations, T max, were observed at 1.5 to 2 hours), and are widely
(>92%) distributed in blood and tissues; good evidence exists that it
crosses blood-brain barriers. Zolpidem is rapidly metabolized to inactive
metabolites, which are eliminated mainly by renal excretion.
Excretion: Most of it undergoes renal
excretion, with an elimination half-life of 2-3 hours.
Uses of HYPNITE-1
HYPNITE-1 is used to treat Insomnia (Not
having enough sleep) which may cause you issues to slide in sleep. This is
useful for helping patients get to sleep faster, reducing the frequency and
duration of middle-of-the-night wakings, and improving the consolidation of
sleep. This implies that due to its fast-paced impact, it is useful for
patients who find difficulty in falling asleep.
Indications
Primary insomnia with onset problems
Short-term treatment of insomnia Dosage and Administration of Yohimbine
Dosage:
In adults, an initial dosage of 5 to 10 mg once per night immediately before
sleep is recommended. Dosage should be individualized according to patient
response and tolerability. Lower dose - to decrease the chance of side effects
in a frail or elderly patient, provide 5 mg daily.
However, to
achieve maximum results or effect of HYPNITE-1, it should be administered on an
empty stomach. The tablet should be taken with a glass of water, follow the
given instructions, and must not chewed crushed, or committed. Patients are
required to get 7-8 hours in bed; otherwise, daytime impairment is
expected.
Side Effects
Common Side Effects:
- Drowsiness
- Dizziness
- Headache
- Upset stomach (nausea or diarrhea)
- Fatigue
Precautions and Warnings
- Pregnancy: HYPNITE-1 should be used in women
who are pregnant only if the potential benefit justifies the potential risk to
the fetus. 12:21 Lisa Zolpidem Pregnancy Category C; zolpidem is secreted in
breast milk, caution advised with breastfeeding mothers Special populations
Geriatric No dose adjustment necessary, but the premature hypotensive or
sedative responses (MGHB and correspondingly for those less than 30 minutes
later, primarily to too much discomfort because of anemia) Falls should not be
used in geriatric patients more than the recommended limits into a meal.
- Dependence: Zolpidem has the potential for
abuse; use caution in patients with a history of substance abuse (also see
Previous Substance Abuse under Cautions). Adj. Renal or hepatic impairment
(potential dose adjustment) (consider: Dose adjustment is likely to be needed
in impaired renal and hepatic function.)
Storage and Handling
Storage of HYPNITE-1 Tablets Store medicine out of the reach of children
and pets
Conclusion
This study demonstrated that HYPNITE-1 was effective when used for the
short-term management of insomnia, as it improved both sleep quality and
duration in patients. One is that it must be selected in a patient-specific
fashion, and care must be taken to avoid both interactions and side effects so
if appropriate, this may eventually lead to increased use
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$10.00
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