Introduction

Febutaz-80 mg - Gout, Hyperuricemia and Avoid These Ingredients while Febutaz 80mg The in vitro potency of the xanthine oxidase inhibitor febuxostat is very high concerning lowering serum urate concentrations. A detailed article on pharmacology, therapeutic uses, and doses of Febutaz-80 mg as well as side effects and precautions.

Pharmacology of Febuxostat

Febutaz-80 mg Mechanism: Febutz-80 mg contains the active ingredient Febuxostat, which is a xanthine oxidase inhibitor. Xanthine oxidase is the enzyme that catalyzes the breakdown of hypoxanthine to xanthine and later on it breaks down Xanthine into Uric acid. Febuxostat, a non-purine antagonist that is responsible for reduced production of uric acid with the inhibition first enzyme xanthine oxidase in the purine catabolic pathway so produces less UA same as Allopurinol but it lowers Serum Uric Acid level inclusive Proc

Therapeutic Uses

1.       Control Gout: Gout is an arthritic problem that occurs due to the deposition of minute collections of urate crystals within a joint or j25oints and causes palate foot, warmth, and inflammation. These are used to control and treat a gout attack by lowering the body output of uric acid.

2.       Febutaz-80mg is indicated in patients with chronic hyperuricemia or elevated uric acid levels in the long term (see WARNINGS, OVERDOSAGE, AND PRECAUTIONS) and serious conditions as follows; Urate renal calculi, when urate levels are high and Uricosuric drugs alone cannot reduce urate levels Some patients who cannot tolerate or whose hyperuricemia is inadequately controlled with treatment with allopurinol.

Dosage and Administration

Dosing (Adults): The usually recommended initial dose of Febutaz-80 mg is one tablet once daily. The dose can be varied according to the plasma levels of uric acid and the patient's clinical response. Dosing and Length of Therapy Dosing OFIRMEV may be administered as an intravenous or intramuscular injection, lasting no longer than 5 to 10 minutes and 15 seconds, respectively.

1.       Sometimes uric acid levels are measured after the first week of the VIAGRA initial dose (40 mg once daily) and the dose is increased to 80 mg once daily if uric acid levels are not significantly reduced.

2.       Standard dose - 80 mg once daily, but may be increased to 120 mg daily based on clinical response and uric acid levels.

Side Effects

Not everybody gets side effects with Febutaz-80 mg similar to any form of medication Common side effects include:

1.       Elevated liver enzymes are liver function abnormalities, which can be a side effect. During treatment, liver function should be monitored regularly.

2.       Nausea: An upset stomach from taking the medication can usually be resolved by taking the medication with food.

3.       Arthralgia: During the administration of Febutaz-80 mg for the management of gout, some patients may still develop arthralgia.

4.       Rash: Rashes of the skin can develop (as well as certain other skin eruptions), and should be taken up with a healthcare provider if they develop and persist

5.       Cardiovascular Events: Due to reports of cardiovascular events; caution should be used when treating certain patients and used only when an adequate safe treatment with allopurinol cannot be tolerated.

Precautions

1.     If you have ever had a heart attack or cerebrovascular disease (which is a disease of the heart or blood vessels) before you start taking Febutaz-80 mg because some of the treatments due to this drug carry an increased risk of heart attack.

2.       Hepatic Function: Monitor LFTs due to the potential for transaminase elevations with febuxostat.

3.       Kidney function - if your kidneys are not working properly this can be worth considering for a dose change or alternative medicine.

4.       Allergy: Severe reactions to injections such as facial swelling, lip swelling or other symptoms relating to the respiratory (throat), and lymphatic system must seek medical attention right away.

 Drug Interactions

Patients are to notify their doctor of all the drugs they are currently taking both the drugs they are taking with prescription, and medications available over-the-counter and place them also to supplements. Notable interactions include:

1.       Azathioprine: Allopurinol should be avoided in patients who are receiving azathioprine, as the concomitant use of these agents may increase the toxicity of azathioprine.

2.       Mercaptopurine - febuxostat can elevate levels of mercaptopurine and cause toxicity as above described with azathioprine.

3.       Interaction Class: Serious Precautions Theophylline (respiratory drug) Theophylline: Buxostat may decrease the serum concentration of theophylline.

Conclusion

Febutaz 80mg is the choice of drug for patients with Gout and Hyperuricemia. Febuxostat helps to lower the level of uric acid in your blood (hyperuricemia) which is common in patients who suffer from gout so they are more likely to experience gout attacks and other problems that are related to excess uric acid levels in their blood. Generally, relatively non-toxic patients should be warned of the potential side effects of the drugs and contacted regularly for conservative management during ongoing therapy. Taking this medication with counseling and lifestyle/diet changes can allow for much better management of gout and hyperuricemia which will ultimately increase the patient's quality of life. Ask your physician for medical guidance tailored to you and your issue