Inhouse product
Celkeran 2
mg Tablet:
Celkeran 2 mg is used in the treatment of a few
types of cancer, for example, CLL: Chronic Lymphocytic Leukemia CLL is a cancer
of the blood that begins in the bone marrow. Celkeran is the commonly used
response for the remedy of WG; this medicine is skilled to back off the course
of the disease. Hodgkin's Lymphoma: Lymphatic system cancer. Celkeran is also
used with additional prescription medications to treat Hodgkin's lymphoma prior
approaches versus more formidable treatments.
Non-Hodgkin's
Lymphoma (NHL): Chlorambucil, with brand names Ledactin and Leukeran, is also
used to treat NHL, but the disease indication is expanded to all forms of NHL,
a big group of closely related blood cancers that are a type of lymphatic
cancer. Here, its place is indispensable when other treatments are ineffective
or contraindicated. Protein macroglobulinemia of Waldenström: Celkeran is used
to manage a rare kind of cancer that results from the production of many
abnormal white blood elements; the drug can aid in symptom control, and
prevention of white blood cell progression in blood.
Mechanism of
Action
Cellkeran
attaches to the DNA in cancer cells, causing cross-links that interfere with
DNA replication. citation needed] By blocking this key process, Celkeran can effectively inhibit the further proliferation of cancer cells leading
to cell death. This is how Celkeran gets automatically classified as an
alkylating agent: a class of chemotherapy drugs famous for their aid in
breaking down the DNA of rapidly multiplying cells.
Administration and Dosage
Celkeran 2 mg Oral Administration is
accompanied by a meal, a daily dose with a glass of water at the same time, every
day. The dose and the way it is given depend on the type and stage of cancer
being treated, how well the patient is overall, and how they respond to the
treatment. Patients should religiously adhere to the instructions from their
oncologist. The tablets must be swallowed whole with water and may be
completely taken with or without food.
Others include as it makes you more
likely to get infections-Tiredness-Hair loss or bruising
easily-Nausea, vomiting, or diarrhea Hematologic Common (1% to 10%): Bone marrow
suppression (asymptomatic decreases in WBC White Blood Cell count), These
include Pancytopenia, febrile neutropenia, leukopenia, granulocytopenia,
anemia, lymphopenia, 1. Some of the problems of the digestive system:
Chemotherapy can cause nausea, vomiting, and diarrhea and people could even lose
their appetite due to chemo. Oral lesions: These cause painful mouth ulcers,
which can make eating difficult. DermatologicalEffects:AllergicSkinRashes:
Erythema multiforme, Stevens - Johnsonincludmg Occasionalcases
of:CutaneousSpasm, Dermatitis, Urticaria161r Combixmtion,Sialorrhea.
Patient Considerations Seek medical history with your doctor to discuss drugs that may interact with the
combination of Celkeran. The blood count will need to be checked regularly, and
your liver function will also be measured on these occasions. Should you
develop any of these symptoms - see your doctor without delay. Develop any side
effects; inform your doctor. Do not use Celkeran during pregnancy. It could
harm a fetus. Must be willing to use contraception during treatment and for an
appropriate period after the last dose.
Conclusion
Celkeran 2 mg is a powerful chemotherapy
medication that is used to treat types of cancer such as CLL, Hodgkin's
lymphoma, NHL, and Waldenström's macroglobulinemia. It does so by blocking DNA
replication, a key process where cancerous cells multiply. Although it provides
great advantages in the treatment of cancer like everything in life it has
a plethora of possible adverse effects that need to be closely watched and
managed. If you are given Celkeran, work with your healthcare team to ensure
you experience an optimal outcome and work to manage any side effects that may
occur.
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